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A prespecified analysis of this trial showed that a greater weight loss was associated with greater improvements in HF-related symptoms and physical limitations, regardless of patients age, gender and baseline body weight 89

However, in some cases, it progresses and causes complications, such as organ failure (mainly in the liver and kidney) [6], septic shock, pulmonary edema, severe pneumonia, and ARDS, which eventually may lead to death [7]

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